Target List
Bone Cancer
EWSR1-ATF1, EWSR1-ERG, EWSR1-ETV1, EWSR1-ETV4, EWSR1-FEV, EWSR1-FLI1
Breast Cancer
CRTC1-MAML2, EML4-ALK, ETV6-NTRK3 (TEL-NTRK3), FGFR1-ZNF703, RAF1-DAZL
Clear Cell Sarcoma
EWSR1-ATF1, EWSR1-CREB1
Central Nervous System Cancer
CLCN6-BRAF, EWSR1-FLI1, FAM131B-BRAF, FGFR1-TACC1, FGFR3-TACC3, GNAI1-BRAF, GOPC-ROS1, MKRN1-BRAF, RNF130-BRAF, SRGAP3-RAF1
Colorectal Cancer
EML4-ALK, ETV6-NTRK3 (TEL-NTRK3), LMNA-NTRK1, TPM3-NTRK1, VTI1A-TCF7L2
Ewing's Sarcoma
EWSR1-ERG, EWSR1-ETV1, EWSR1-ETV4, EWSR1-FEV, EWSR1-FLI1
Gastric Cancer
SLC34A2-ROS1, SND1-BRAF
Glioma
GOPC-ROS1, SRGAP3-RAF1
Inflammatory Myofibroblastic Tumor
ATIC-ALK, CARS-ALK, CLTC-ALK, RANBP2-ALK, SEC31A-ALK, TPM3-ALK, TPM4-ALK
Kidney Cancer
ASPSCR1-TFE3, ETV6-NTRK3 (TEL-NTRK3), PRCC-TFE3, VCL-ALK
Leukemia
Acute Lymphoblastic Leukemia
BCR-ABL1, BCR-JAK2, EML1-ABL1, ETV6-ABL2 (TEL-ABL2), ETV6-JAK2 (TEL-JAK2), ETV6-NCOA2 (TEL-NCOA2), ETV6-RUNX1 (TEL-AML1), EWSR1-ZNF384 (EWSR1-CIZ), FGFR1OP-FGFR1, JAK2-PAX5, KMT2A-ACTN4 (MLL-ACTN4), KMT2A-AFF1 (MLL-AF4, MLL-MLLT2), KMT2A-AFF3 (MLL-LAF4), KMT2A-CASC5 (MLL-CASC5), KMT2A-EPS15 (MLL-EPS15), KMT2A-FOXO4 (MLL-AFX), KMT2A-FRYL (MLL-FRYL), KMT2A-GAS7 (MLL-GAS7), KMT2A-GPHN (MLL-GPHN), KMT2A-MLLT1 (MLL-ENL), KMT2A-MLLT10 (MLL-AF10), KMT2A-MLLT3 (MLL-AF9), KMT2A-AFDN (MLL-AF6), KMT2A-TET1 (MLL-TET1), MNX1-ETV6 (HLBX9-TEL), NUP214-ABL1, NUP98-LNP1 (NUP98-LOC348801), NUP98-RAP1GDS1, P2RY8-CRLF2, PAX5-AUTS2, PAX5-ELN, PAX5-ETV6 (PAX5-TEL), PAX5-FOXP1, PAX5-JAK2, PAX5-PML, PCM1-JAK2, PICALM-MLLT10 (PICALM-AF10, CALM-AF10), RCSD1-ABL1, SET-NUP214, SFPQ-ABL1, STIL-TAL1 (SIL-TAL1), TAF15-ZNF384 (TAF15-CIZ), TCF3-HLF (E2A-HLF), TCF3-PBX1 (E2A-PBX1), ZMIZ1-ABL1
Acute Myeloid Leukemia
BCOR-RARA, BCR-JAK2, CBFA2T3-GLIS2, CBFB-MYH11, CCDC88C-PDGFRB (KIAA1509-PDGFRB), CHIC2-ETV6 (BTL-ETV6), DEK-NUP214 (DEK-CAN), DHH-RHEBL1, ETV6-NCOA2 (TEL-NCOA2), ETV6-NTRK3 (TEL-NTRK3), ETV6-PDGFRB (TEL-PDGFRB), ETV6-PTPRR (TEL-PTPRR), ETV6-RUNX1 (TEL-AML1), FIP1L1-PDGFRA, FIP1L1-RARA, FUS-ERG, KAT6A-CREBBP (MOZ-CBP), KAT6A-EP300 (MOZ-P300), KAT6A-NCOA2 (MOZ-TIF2), KMT2A-ABI1 (MLL-ABI1), KMT2A-ARHGAP26 (MLL-GRAF), KMT2A-ARHGEF12 (MLL-LARG), KMT2A-CASC5 (MLL-CASC5), KMT2A-CBL (MLL-CBL), KMT2A-CEP170B (MLL-CEP170B, MLL-KIAA0284), KMT2A-CREBBP (MLL-CBP), KMT2A-ELL (MLL-ELL), KMT2A-EP300 (MLL-EP300), KMT2A-EPS15 (MLL-EPS15), KMT2A-FNBP1 (MLL-FNBP1, MLL-FBP17), KMT2A-FOXO4 (MLL-AFX), KMT2A-FRYL (MLL-FRYL), KMT2A-GAS7 (MLL-GAS7), KMT2A-GPHN (MLL-GPHN), KMT2A-MAML2 (MLL-MAML2), KMT2A-MLLT1 (MLL-ENL), KMT2A-MLLT10 (MLL-AF10), KMT2A-MLLT11 (MLL-AF1Q), KMT2A-MLLT3 (MLL-AF9), KMT2A-AFDN (MLL-AF6), KMT2A-MLLT6 (MLL-AF17), KMT2A-MYO1F (MLL-MYO1F), KMT2A-SEPT2 (MLL-SEPT2), KMT2A-SEPT5 (MLL-SEPT5), KMT2A-SEPT6 (MLL-SEPT6), KMT2A-SEPT9 (MLL-SEPT9), KMT2A-TET1 (MLL-TET1), MN1-ETV6 (MN1-TEL), MNX1-ETV6 (HLBX9-TEL), MYB-GATA1, NPM1-MLF1, NPM1-RARA, NUMA1-RARA (NUMA-RARA), NUP98-DDX10, NUP98-HOXA9, NUP98-HOXD13, NUP98-KDM5A (NUP98-JARID1A), NUP98-LNP1 (NUP98-LOC348801), NUP98-NSD1, NUP98-PHF23, NUP98-PRRX1 (NUP98-PMX1), NUP98-PSIP1 (NUP98-LEDGF), NUP98-TOP1, NUP98-WHSC1L1 (NUP98-NSD3), PCM1-JAK2, PICALM-MLLT10 (PICALM-AF10, CALM-AF10), PML-RARA, RANBP2-ALK, RBM15-MKL1 (OTT-MAL), RPN1-MECOM (RPN1-EVI1), RUNX1-CBFA2T3 (AML1-CBFA2T3), RUNX1-MECOM (AML1-MDS1-EVI1), RUNX1-PRDM16 (AML1-PRDM16), RUNX1-RPL22, RUNX1-RUNX1T1 (AML1-ETO), RUNX1-USP42 (AML1-USP42), SET-NUP214, STAT5B-RARA, TAF15-ZNF384 (TAF15-CIZ), TRIP11-PDGFRB (CEV14-PDGFRB), ZBTB16-RARA (PLZF-RARA)
Chronic Myeloid Leukemia
BCR-ABL1, BCR-JAK2, CCDC88C-PDGFRB (KIAA1509-PDGFRB), NDE1-PDGFRB, RUNX1-MECOM (AML1-MDS1-EVI1)
Myeloproliferative Neoplasms
BCR-FGFR1, BCR-JAK2, BCR-PDGFRA, CNTRL-FGFR1 (CEP110-FGFR1), ETV6-ABL1 (TEL-ABL1), ETV6-FLT3 (TEL-FLT3), ETV6-JAK2 (TEL-JAK2), ETV6-MECOM (TEL-MDS1-EVI1), ETV6-PDGFRB (TEL-PDGFRB), FGFR1OP-FGFR1, FIP1L1-RARA, MN1-ETV6 (MN1-TEL), NPM1-MLF1, NUP98-HOXA9, NUP98-HOXD13, NUP98-PSIP1 (NUP98-LEDGF), PRKG2-PDGFRB, RUNX1-MECOM (AML1-MDS1-EVI1)
Myelodysplastic Syndromes
DEK-NUP214 (DEK-CAN), ETV6-GOT1 (TEL-GOT1), ETV6-JAK2 (TEL-JAK2), ETV6-PTPRR (TEL-PTPRR), KMT2A-ACTN4 (MLL-ACTN4), KMT2A-CASC5 (MLL-CASC5), KMT2A-FRYL (MLL-FRYL), KMT2A-MAML2 (MLL-MAML2), MN1-ETV6 (MN1-TEL), MNX1-ETV6 (HLBX9-TEL), NDE1-PDGFRB, NPM1-MLF1, NUP98-HOXD13, NUP98-LNP1 (NUP98-LOC348801), NUP98-TOP1, PCM1-JAK2, RUNX1-MECOM (AML1-MDS1-EVI1), RUNX1-PRDM16 (AML1-PRDM16), ZMYM2-FGFR1
Lymphoma
ALK-MSN, ATIC-ALK, BIRC3-MALT1, CLTC-ALK, ETV6-FGFR3, MSN-ALK, NPM1-ALK, SQSTM1-ALK, TFG-ALK, TPM3-ALK, TPM4-ALK
Liver Cancer
FGFR2-CCDC6, FGFR2-TACC3
Lung Cancer
CCDC6-RET, CD74-NRG1, CD74-NTRK1, CD74-ROS1, CRTC1-MAML2, CUX1-RET, EML4-ALK, EZR-ROS1, FGFR3-TACC3, GOPC-ROS1, KIF5B-ALK, KIF5B-RET, KLC1-ALK, LRIG3-ROS1, MPRIP-NTRK1, NCOA4-RET, SDC4-ROS1, SLC34A2-ROS1, SND1-BRAF, STRN-ALK, TFG-ALK, TPM3-ROS1, TRIM33-RET
Melanoma
AGK-BRAF, EWSR1-ATF1, EWSR1-CREB1, PAPSS1-BRAF, TRIM24-BRAF
Non-Small Cell Lung Cancer
BAG4-FGFR1, CCDC6-RET, CD74-NRG1, CD74-ROS1, EML4-ALK, EZR-ROS1, GOPC-ROS1, HIP1-ALK, KIF5B-ALK, KIF5B-RET, KLC1-ALK, LRIG3-ROS1, SDC4-ROS1, SLC34A2-ROS1, STRN-ALK, TFG-ALK, TPM3-ROS1, TPR-ALK, TRIM33-RET
Pancreatic Cancer
EWSR1-FLI1, GATM-BRAF, HACL1-RAF1, HERPUD1-BRAF, SND1-BRAF, ZSCAN30-BRAF
Prostate Cancer
ESRP1-RAF1, RAF1-ESRP1, SLC45A3-BRAF, SND1-BRAF, TMPRSS2-ERG, UBE2L3-KRAS
Salivary Gland Cancer
CRTC1-MAML2, ETV6-NTRK3 (TEL-NTRK3), FGFR1-PLAG1
Sarcomas
ASPSCR1-TFE3, COL1A1-PDGFB, ETV6-NTRK3 (TEL-NTRK3), EWSR1-DDIT3, EWSR1-WT1, FUS-DDIT3, LMNA-NTRK1, NPM1-ALK, PAX3-FOXO1, PAX7-FOXO1, SS18-SSX1, SS18-SSX2
Skin Cancer
CEP89-BRAF, CRTC1-MAML2, ERC1-ROS1, EWSR1-ATF1, FCHSD1-BRAF, GOLGA5-RET, KIF5B-RET, LSM14A-BRAF, MYO5A-ROS1, PPFIBP1-ROS1, PWWP2A-ROS1, SQSTM1-ALK, TPM3-ALK
Soft Tissue Cancer
ASPSCR1-TFE3, ATIC-ALK, CARS-ALK, CLTC-ALK, COL1A1-PDGFB, DCTN1-ALK, ETV6-NTRK3 (TEL-NTRK3), EWSR1-ATF1, EWSR1-CREB1, EWSR1-DDIT3, EWSR1-ERG, EWSR1-ETV1, EWSR1-ETV4, EWSR1-FEV, EWSR1-FLI1, EWSR1-WT1, FN1-ALK, FUS-DDIT3, NCOA4-RET, PAX3-FOXO1, PAX7-FOXO1, PPFIBP1-ALK, RANBP2-ALK, SEC31A-ALK, SS18-SSX1, SS18-SSX2, TPM3-ALK, TPM4-ALK
Thyroid Cancer
AKAP9-BRAF, CCDC6-RET, CRTC1-MAML2, EML4-ALK, ERC1-RET, ETV6-NTRK3 (TEL-NTRK3), GOLGA5-RET, HOOK3-RET, NCOA4-RET, NTRK1-TFG, NTRK1-TPM3, PAX8-PPARG, PCM1-RET, PRKAR1A-RET, RET-GOLGA5, STRN-ALK, TFG-NTRK1, TPM3-NTRK1, TRIM24-RET, TRIM27-RET, TRIM33-RET
Urinary Tract Cancer
FGFR3-BAIAP2L1, FGFR3-TACC3