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GeneGlobe ID: PAHS-3401Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT

RT2 Profiler PCR Array

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Product Specification

Target List

Apoptosis
ABL1AKT1APAF1BADBAK1BAXBCL2BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L11BIDBIRC3 (c-IAP2)CASP1 (ICE)CASP3CASP7CASP8 (FLICE)CASP9CD40 (TNFRSF5)CD40LGCFLAR (CASPER)FADDFASFASLG (TNFSF6)GADD45AMCL1TNFTNFRSF10A (TRAIL-R)TNFRSF10B (DR5)TNFRSF1A (TNFR1)TNFSF10 (TRAIL)TP53 (p53)XIAP
Necrosis
ATP6V1G2BMFCCDC103CD300LDCLEC18ACOMMD4CYLDDEFB1DPYSL4EIF5BFOXI1GALNT5GRB2HOXA3HSPBAP1JPH3KCNIP1MAGNUDT13OR10J3PARP2PVRRAB25S100A7ASPATA2SYCP2MACO1TNFAIP8L1TNFRSF1A (TNFR1)TXNL4B
DNA Damage & Repair
APEX1ATMATRBRCA1BRCA2CDKN1A (p21CIP1, WAF1)CHEK1CHEK2 (RAD53)DDIT3 (GADD153, CHOP)ERCC1ERCC2 (XPD)ERCC3 (XPB)ERCC5ERCC6GADD45ALIG4MDM2MGMT (AGT)MLH1MSH2OGG1PARP1 (ADPRT1)PCNAPRKDCRAD51TP53 (p53)XPAXPCXRCC1XRCC5
Mitochondrial Energy Metabolism
ACLYACO1ACO2COX6B1COX8ACSCYC1DLDDLSTFHIDH1IDH2IDH3AIDH3BIDH3GMDH1MDH1BMDH2OGDHSDHASDHBSDHCSDHDSUCLA2SUCLG1SUCLG2UCP1UCP2UCP3
Fatty Acid Metabolism
ACAA1ACAA2ACAD11ACAD9ACADLACADMACADSACADSBACADVLACAT1ACAT2ACOT1ACOT12ACOT6ACOT7ACOT8ACOT9ACOX1ACOX2ACOX3BDH2CPT1ACPT1BCPT2CRATCROTDECR1ECHS1EHHADHGCDHHADHA
Oxidative Stress & Antioxidant Response
AASSCATCTSBDHCR24DUOX1DUOX2EPXGPX1GPX2GPX3GPX4GPX5GPX6GPX7IDH1MPONQO1NUDT1NUDT15PPP1R15BPRDX1PRDX2PRDX6 (AOP2)SOD1TPOTXNIPTXNRD2UCP3
Heat Shock Response
CRYAACRYABDNAJA1DNAJA2DNAJA3DNAJB1DNAJB6DNAJC3DNAJC5DNAJC6HSF1 (TCF5)HSF2HSP90AA1HSP90AB1HSP90B1HSPA1A (HSP70-1A)HSPA1BHSPA1LHSPA2HSPA4 (HSP70)HSPA5 (GRP78)HSPA8HSPA9HSPB1 (HSP27)HSPB2HSPB6HSPB8HSPD1HSPE1HSPH1 (HSP105)TCP1
Endoplasmic Reticulum Stress & Unfolded Protein Response
AMFRATF4ATF6BAXDDIT3 (GADD153, CHOP)DERL1EDEM1EDEM3EIF2AK3ERN2ERO1A (ERO1L)ERO1B (ERO1LB)FBXO6GADD45AHERPUD1HTRA2HTRA4MBTPS1MBTPS2NPLOC4NUCB1OS9PFDN5SEC62SEL1LSELENOSSERP1SYVN1UBE2G2UBE2J2UBXN4VCPXBP1
Cytochrome P450s & Phase I Drug Metabolism
CYP1A1CYP1A2CYP2B6CYP2C19CYP2C9CYP2D6CYP2E1CYP3A4ESDFMO2FMO3FMO4FMO5MAOAMAOB
Steatosis
ACACAADKALDH2AQP4CD36COMTCYP2E1CYP7B1DNM1ENO1FASFASNGPD1HAAOHADHBKHKLMNALPLLY6DMAPK8 (JNK1)MTTPPCCAPNPLA3PPARARETNSCDSREBF1SYT1TFF3VCP
Cholestasis
ABCB1 (MDR1, PGY1)ABCB4ABCC1 (MRP1)ABCC2 (MRP2, cMOAT)ABCC3 (MRP3, MOAT-D)APOEATP8B1CYP3A4CYP7A1DLATESR1 (ERα)HLA-DRB1ICAM1IL10IL1BIL2IL6JAG1MPONR1H4NUP210SLC51ASLC51BPDYNRDXSLC10A1TGFB1TNF
Phospholipidosis
ABCB1 (MDR1, PGY1)ALDH1A1 (RALDH1)ASAH1ASNSCES2CTSBEPHX1FABP1TIMM10BGSTM4HPNINHBELSSMANBAMLXMRPS18BNR0B2PORS100A8MSMO1SERPINA3SLC2A3SLCO1A2SMPD1STBD1TAGLNUGT1A1UGT2A1UGT2B4WIPI1
Immunotoxicity
ADH1CAHRAHSGALBAPOA5APOFC3C9CASP3CD19CD4CD44CD80CD86CD8ACTSECYP1A1CYP3A4EP300F2 (Thrombin)FABP1FASGPTGSTA3HPXHRGHSPA5 (GRP78)IFNA1IFNGIL10IL13IL1AIL1BIL2IL4IL5IL6ITGAXKLF1LYZMETAP2MKI67NFKB1NR5A2PON1POU3F3PTGS2 (COX2)PTPRCSOD1TNFTRIM10UBQLN2

Product Resources

Gene Table for 384-well Array
File Size: 185.27 KBLanguage: English

Resources

Supplementary Protocols (10)
ABI 7500 & ABI 7500 FAST (Software Version 2.0.4) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (388KB)
ABI 7900HT (for SDS Software 2.1, 2.3 and 2.4) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (320KB)
ABI StepOnePlus (for Software Version 2.0) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (77KB)
Bio-Rad CFX96 and CFX384 instrument setup instructions for RT2 Profiler PCR Arrays
PDF (298KB)
Bio-Rad iCycler & iQ Real-Time PCR Systems (for Software Version 3.1) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (249KB)
Eppendorf Mastercycler ep realplex instrument setup instructions for RT2 Profiler PCR Arrays
PDF (554KB)
Stratagene Mx3000P qPCR System real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (259KB)
Rotor-Gene Q real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (175KB)
Roche LightCycler 480 real-time PCR run setup instructions for RT2 Profiler PCR Arrays
PDF (1MB)
Life Technologies ViiA7 (ViiA 7 Software v1.2) instrument setup instructions for RT2 Profiler PCR Arrays
PDF (511KB)
Brochures & Guides (3)
RT2 Profiler PCR Arrays: Pathway Analysis - (EN)
PDF (1MB)
Total RNA Discovery - (EN)
PDF (255KB)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Technical Guide to QIAGEN PCR Arrays
PDF (2MB)
Safety Data Sheets (1)
Safety Data Sheets
Articles (17)
(EN) Control of PPARγ and mTOR in insulin resistance
(EN) miRNA regulation of angiogenesis: new roles for IGF-1R signaling and heparin
(EN) Regulation of BAX mediated apoptosis by BCL2 family members
(EN) Chemokines: manipulators of metastasis
(EN) DNA damage repair — regulation through autophagy
(EN) Silencing cell-cell communication to combat drug toxicity
(EN) Cellular stress, TGF-β, and EMT: what are the true origins of fibrosis?
(EN) The role of inflammation in cancer
(EN) What enhances the inflammatory response: new players and unexpected roles
(EN) Induced pluripotent stem cells: real stem cells?
(EN) Lipid autophagy in obesity and atherosclerosis: chewing the fat
(EN)Metabolic homeostasis: regulation of FOXO by class IIa HDACs
(EN)Regulation of the extracellular matrix by miRNA: impact on cancer metastases
(EN)Inflammation and neurodegenerative disease: a role for the estrogen receptor in suppression of inflammation in the brain
(EN)A good transcription factor gone rogue: the two faces of NRF2 in oxidative stress
(EN)Managing mortality: how cells regulate telomerase activity
(EN) Master Regulators Direct TGF-beta and Smad Signaling in Different Cell Types
Download Files (3)
Housekeeping Gene Data Analysis
XLSX (60KB)
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

RT2 Profiler PCR Array Data Analysis v3.5 Handbook
PDF (770KB)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Scientific Posters (1)
Explore the RNA Universe!
PDF (1MB)
Poster for download
Kit Handbooks (1)
RT2 Profiler PCR Array Handbook
PDF (702KB)
For pathway-focused gene expression profiling using real-time RT-PCR
Performance Data (7)
PCR_Array_4x96_384-Well_Conversion Spreadsheet
XLSX (38KB)
RT2 Profiler Housekeeping Genes PCR Array Data Analysis 1808
XLSX (65KB)
RT2 Profiler PCR Array 384HT Data Analysis Spreadsheet 1808
XLSX (1MB)
RT2 Profiler PCR Array Data Analysis Spreadsheet 1904
XLSX (3MB)
RT2 Profiler RNA QC PCR Array Data Analysis Spreadsheet 1808
XLSX (60KB)
RT2 qPCR Assay Data Analysis 1808 Spreadsheet
XLSX (104KB)
Universal Custom PCR Array Conversion
XLSX (291KB)
Instrument Technical Documents (2)
(EN) - RT2 Profiler PCR Arrays
PDF (431KB)
For pathway-focused gene expression analysis
QIAGEN Service Core - (EN)
PDF (333KB)
For gene expression and genomic analysis
White Papers (2)
RT2 Profiler PCR Arrays: Pathway-focused gene expression profiling with qRT-PCR
PDF (1MB)
RT2 Profiler PCR Array application examples
PDF (563KB)
Gene Expression Analysis (1)
(EN) Wnt Signaling: GSK3 Inhibition Through Sequestration in Multivesicular Bodies
Certificates of Analysis (1)
Certificates of Analysis
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Introducing the RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT, a cutting-edge addition to our RT2 Profiler PCR Arrays lineup, specifically designed for Real-Time PCR applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting Real-Time PCR, or any other sophisticated analyses, this product from our RT2 Profiler PCR Arrays collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT and elevate your work to new heights.
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