GeneGlobe ID: PAHS-3401Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT

RT2 Profiler PCR Array

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Product Specification

Target List

Apoptosis
ABL1, AKT1, APAF1, BAD, BAK1, BAX, BCL2, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L11, BID, BIRC3 (c-IAP2), CASP1 (ICE), CASP3, CASP7, CASP8 (FLICE), CASP9, CD40 (TNFRSF5), CD40LG, CFLAR (CASPER), FADD, FAS, FASLG (TNFSF6), GADD45A, MCL1, TNF, TNFRSF10A (TRAIL-R), TNFRSF10B (DR5), TNFRSF1A (TNFR1), TNFSF10 (TRAIL), TP53 (p53), XIAP
Necrosis
ATP6V1G2, BMF, CCDC103, CD300LD, CLEC18A, COMMD4, CYLD, DEFB1, DPYSL4, EIF5B, FOXI1, GALNT5, GRB2, HOXA3, HSPBAP1, JPH3, KCNIP1, MAG, NUDT13, OR10J3, PARP2, PVR, RAB25, S100A7A, SPATA2, SYCP2, MACO1, TNFAIP8L1, TNFRSF1A (TNFR1), TXNL4B
DNA Damage & Repair
APEX1, ATM, ATR, BRCA1, BRCA2, CDKN1A (p21CIP1, WAF1), CHEK1, CHEK2 (RAD53), DDIT3 (GADD153, CHOP), ERCC1, ERCC2 (XPD), ERCC3 (XPB), ERCC5, ERCC6, GADD45A, LIG4, MDM2, MGMT (AGT), MLH1, MSH2, OGG1, PARP1 (ADPRT1), PCNA, PRKDC, RAD51, TP53 (p53), XPA, XPC, XRCC1, XRCC5
Mitochondrial Energy Metabolism
ACLY, ACO1, ACO2, COX6B1, COX8A, CS, CYC1, DLD, DLST, FH, IDH1, IDH2, IDH3A, IDH3B, IDH3G, MDH1, MDH1B, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SUCLA2, SUCLG1, SUCLG2, UCP1, UCP2, UCP3
Fatty Acid Metabolism
ACAA1, ACAA2, ACAD11, ACAD9, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACAT1, ACAT2, ACOT1, ACOT12, ACOT6, ACOT7, ACOT8, ACOT9, ACOX1, ACOX2, ACOX3, BDH2, CPT1A, CPT1B, CPT2, CRAT, CROT, DECR1, ECHS1, EHHADH, GCDH, HADHA
Oxidative Stress & Antioxidant Response
AASS, CAT, CTSB, DHCR24, DUOX1, DUOX2, EPX, GPX1, GPX2, GPX3, GPX4, GPX5, GPX6, GPX7, IDH1, MPO, NQO1, NUDT1, NUDT15, PPP1R15B, PRDX1, PRDX2, PRDX6 (AOP2), SOD1, TPO, TXNIP, TXNRD2, UCP3
Heat Shock Response
CRYAA, CRYAB, DNAJA1, DNAJA2, DNAJA3, DNAJB1, DNAJB6, DNAJC3, DNAJC5, DNAJC6, HSF1 (TCF5), HSF2, HSP90AA1, HSP90AB1, HSP90B1, HSPA1A (HSP70-1A), HSPA1B, HSPA1L, HSPA2, HSPA4 (HSP70), HSPA5 (GRP78), HSPA8, HSPA9, HSPB1 (HSP27), HSPB2, HSPB6, HSPB8, HSPD1, HSPE1, HSPH1 (HSP105), TCP1
Endoplasmic Reticulum Stress & Unfolded Protein Response
AMFR, ATF4, ATF6, BAX, DDIT3 (GADD153, CHOP), DERL1, EDEM1, EDEM3, EIF2AK3, ERN2, ERO1A (ERO1L), ERO1B (ERO1LB), FBXO6, GADD45A, HERPUD1, HTRA2, HTRA4, MBTPS1, MBTPS2, NPLOC4, NUCB1, OS9, PFDN5, SEC62, SEL1L, SELENOS, SERP1, SYVN1, UBE2G2, UBE2J2, UBXN4, VCP, XBP1
Cytochrome P450s & Phase I Drug Metabolism
CYP1A1, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP2E1, CYP3A4, ESD, FMO2, FMO3, FMO4, FMO5, MAOA, MAOB
Steatosis
ACACA, ADK, ALDH2, AQP4, CD36, COMT, CYP2E1, CYP7B1, DNM1, ENO1, FAS, FASN, GPD1, HAAO, HADHB, KHK, LMNA, LPL, LY6D, MAPK8 (JNK1), MTTP, PCCA, PNPLA3, PPARA, RETN, SCD, SREBF1, SYT1, TFF3, VCP
Cholestasis
ABCB1 (MDR1, PGY1), ABCB4, ABCC1 (MRP1), ABCC2 (MRP2, cMOAT), ABCC3 (MRP3, MOAT-D), APOE, ATP8B1, CYP3A4, CYP7A1, DLAT, ESR1 (ERα), HLA-DRB1, ICAM1, IL10, IL1B, IL2, IL6, JAG1, MPO, NR1H4, NUP210, SLC51A, SLC51B, PDYN, RDX, SLC10A1, TGFB1, TNF
Phospholipidosis
ABCB1 (MDR1, PGY1), ALDH1A1 (RALDH1), ASAH1, ASNS, CES2, CTSB, EPHX1, FABP1, TIMM10B, GSTM4, HPN, INHBE, LSS, MANBA, MLX, MRPS18B, NR0B2, POR, S100A8, MSMO1, SERPINA3, SLC2A3, SLCO1A2, SMPD1, STBD1, TAGLN, UGT1A1, UGT2A1, UGT2B4, WIPI1
Immunotoxicity
ADH1C, AHR, AHSG, ALB, APOA5, APOF, C3, C9, CASP3, CD19, CD4, CD44, CD80, CD86, CD8A, CTSE, CYP1A1, CYP3A4, EP300, F2 (Thrombin), FABP1, FAS, GPT, GSTA3, HPX, HRG, HSPA5 (GRP78), IFNA1, IFNG, IL10, IL13, IL1A, IL1B, IL2, IL4, IL5, IL6, ITGAX, KLF1, LYZ, METAP2, MKI67, NFKB1, NR5A2, PON1, POU3F3, PTGS2 (COX2), PTPRC, SOD1, TNF, TRIM10, UBQLN2

Product Resources

Gene Table for 384-well Array
File Size: 185.27 KBLanguage: English

Resources

Brochures & Guides (3)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Safety Data Sheets (1)
Download Files (3)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Poster for download
Kit Handbooks (1)
For pathway-focused gene expression profiling using real-time RT-PCR
Instrument Technical Documents (2)
For gene expression and genomic analysis
For pathway-focused gene expression analysis
Certificates of Analysis (1)
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Introducing the RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT, a cutting-edge addition to our RT2 Profiler PCR Arrays lineup, specifically designed for Real-Time PCR applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting Real-Time PCR, or any other sophisticated analyses, this product from our RT2 Profiler PCR Arrays collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with RT² Profiler™ PCR Array Human Molecular Toxicology PathwayFinder 384HT and elevate your work to new heights.