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Workflow for library preparation using QIAseq Fusion XP Targeted Panels
High correlation gene expression over a 5-fold difference in RNA input
Outstanding efficiency and sensitivity
High sensitivity SNP/InDel detection
GeneGlobe ID: JHS-001Z | Cat. No.: Varies | QIAseq RNA Fusion XP Panels

QIAseq RNA Fusion XP Leukemia Panel

Product Specification

Kit containing ALL reagents (except indexes) for fusion and gene expression profiling by digital RNAseq

Target List

Covers specific sides of specific exons of the targeted genes based on the Human GRCh38 genome build.Analyzes the expression of the targeted genes.Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build.

Acute Leukemia of Ambiguous Lineage
ABL1AFF1BCRCT45A2ETV6EWSR1GPHNKMT2AMLLT10MN1NUP214PBX1SETTCF3ZNF384
Acute Lymphoblastic Leukemia (ALL)
ABL1ABL2ACTN4AFDNAFF1AFF3AFF4AGGF1ANLNASNSATF7IPAUTS2BCL9BCRBTBD18CASC5CREBBPCSF1RDDX3XEBF1ELLELNEML1EP300EPS15ESRRBETV6EWSR1FGFR1FGFR1OPFLT3FOXO4FOXP1FRYLGAS7GPHNHLFHNRNPUL1INPP5DJAK2KMT2AKMT2ELNP1MAML2MEF2DMLLT1MLLT10MLLT3MN1MNX1MYBMYCNCOA2NOTCH1NUP214NUP98P2RY8PAX5PBX1PCM1PDGFRBPICALMPMLPRDM16RAP1GDS1RARARCSD1RUNX1SALL2SETSFPQSPI1SSBP2STILSTMN1TAF15TAL1TCF3TCF7TET1USP9XZBTB16ZMIZ1ZMYM2ZNF384ZNF521ATMBRAFCDKN2ACREBBPCSF3RDNM2EGFRFBXW7GATA2HRASMAP2K1MLH1PAX5PDGFRAPTENSMARCB1
Acute Myeloid Leukemia (AML)
ABI1ABI2ABL1AFDNAFF1AFF4ALKANLNARHGAP26ARHGEF12BCORBCRCASC5CBFA2T3CBFBCBLCCDC88CCEP170BCHD1CHIC2CREBBPDAB2IPDDX10DEKDHHELLEP300EPS15ERGETV6FGFR1FIP1L1FLNAFNBP1FOXO3FOXO4FRYLFUSGAS7GATA1GLIS2GPHNHAUS1HOXA9HOXC11HOXC13HOXD13IRF2BP2JAK2KAT6AKDM5AKIAA1524KMT2ALASP1LNP1LPPLYNMAML2MECOMMKL1MLF1MLLT1MLLT10MLLT11MLLT3MLLT6MN1MNX1MYBMYH11MYO1FNCKIPSDNCOA2NF1NPM1NSD1NTRK3NUMA1NUP214NUP98PBX1PCM1PDGFRAPDGFRBPDS5APHF23PICALMPMLPRDM16PRRX1PSIP1PTPRRRANBP2RARARBM15RHEBL1RPL22RPN1RUNX1RUNX1T1SARNPSEPT2SEPT5SEPT6SEPT9SETSH3GL1SORBS2STAT5BTAF15TCF3TET1TFGTOP1TOP3ATRIP11UBA2USP42WHSC1L1WTIPZBTB16ZFYVE19ZNF384ASXL1ATMBCORBRAFCDKN2ACHEK2CREBBPCSF3RDAXXDNM2FLT3GATA2IDH1IDH2JAK1JAK3KITKMT2DKRASMAP2K1MPLMYCNRASPBRM1PDGFRAPPM1DPTENPTPN11RAD21RETRUNX1SMARCB1SRSF2U2AF1WT1
Acute Myelomonocytic Leukemia (AMML)
FLNAHOXD13NUP98
B-Cell Acute Lymphoblastic Leukemia (B-ALL)
ABL1ACTN4AFF1AFF3AFF4ATF7IPBCRBTBD18EPS15ERGESRRBETV6EWSR1FUSGAS7JAK2KMT2AMAPRE1MLLT1NUP214P2RY8PAX5PBX1PCM1RUNX1SETSSBP2TCF3USP9XZNF384ZNF521
Blast Phase Chronic Myeloid Leukemia
ABL1BCRETV6JAK2
Chronic Eosinophilic Leukemia
ACSL6TNIP1
Chronic Lymphocytic Leukemia (CLL)
MYCNOTCH1BRAFCHEK2CSF3RMAP2K1TERT
Chronic Myeloid Leukemia (CML)
ABL1BCRCCDC88CETV6JAK2MECOMMN1NDE1NUP98PCM1PDGFRBRUNX1ABL1CDKN2ACREBBPCSF3RFBXW7GATA2
Chronic Myelomonocytic Leukemia (CMML)
CREBBPELLETV6KMT2AMN1CSF3RHRASSRSF2
Myelodysplastic Syndromes (MDS)
ABL1ACTN4ALKCASC5CREBBPDEKERGETV6FRYLFUSHOXD13JAK2KMT2ALNP1MAML2MECOMMLF1MN1MNX1NDE1NPM1NUP214NUP98PCM1PDGFRBPRDM16PTPRRRANBP2RUNX1RUNX1T1TOP1CDKN2ACSF3RETNK1GNASHRASRAD21SETBP1SRSF2U2AF1XPO1ZRSR2
Myeloproliferative Neoplasms
ABL1ACSL6BCRETV6FGFR1FGFR1OPFIP1L1FLT3HOXA9HOXD13JAK2LYNMECOMMLF1MN1NPM1NUP98PDGFRBPRKG2PSIP1RARARUNX1TNIP1ZMYM2ABL1ASXL1JAK2JAK3KRASMPLNRASSETBP1SF3B1SH2B3SRSF2
T-Cell Acute Lymphoblastic Leukemia (T-ALL)
ABL1AFDNAGGF1ASNSBCRCASC5DDX3XETV6JAK2KMT2AKMT2EMLLT1MLLT10NOTCH1NUP214PBX1RUNX1SALL2SETSPI1STILSTMN1TAL1TCF3TCF7
Other Leukemias
IKZF3IRF2BP2MYCNPM1PDCD1LG2SETD2
Commercial Control Samples
ALKBAIAP2L1BRAFCCDC6CD74EGFREML4ERGETV6FGFR3KIF5BLMNAMETNCOA4NTRK1NTRK3PAX8PPARGRETROS1SEPT14SLC34A2SLC45A3TACC3TFGTMPRSS2TPM3
General Leukemia Markers
ANPEPCD19CD200CD33CD34CD38CR2FOXM1FOXO3HOXA9ITGA6KITMS4A1RUNX1
Leukemia Subtype Marker
Acute Lymphoblastic Leukemia (ALL)
ANPEPBTG1CASP8AP2CD19CD1ACD2CD22CD33CD5CD7CD79ACD8ACR2ETV6HLA-DRAHLA-DRB1IL2RAJUNKITLMO1LMO2LYL1MEIS1MMEMS4A1MYCPBX1PTPRCRB1VEGFAWT1
B Cell Acute Lymphoblastic Leukemia (B-ALL)
BTG1CD300ACD72CD79ACD79BCD86CDKN2ACDKN2BCRLF2EBF1ETV6HOXA9IKZF1PAX5RB1
T Cell Acute Lymphoblastic Leukemia (T-ALL)
BTKCD27CD4KCNN4LMO1LMO2LYL1MMP9RUNX1SERPINI1TAL1THBS1TLX1TLX3VPREB3
Acute Myeloid Leukemia (AML)
ADGRE5ASS1BAALCBCL11BBIRC5CD200CD300ACD44CD86CD96CD99CLEC12AERGFCGR2AFLT3HAVCR2IL2RAJUNKITKLF4LEF1MECOMMEIS1MMP9NPM1PTPRCTHBS1VEGFAWT1
Chronic Lymphocytic Leukemia (CLL)
ABCA6AIM2AKT1BAXBCL2BIRC2BTKCD19CD200CD24CD27CD5CD79BCXCR4IL7ITGA4ITGAMJUNKCNN4LAIR1LEF1MCL1MMP9MS4A1ROR1SERPINI1SOX11THBS1TNFTTNVEGFAVPREB3WNT3
Chronic Myeloid Leukemia (CML)
AURKAAURKBIL2RAJUNKITPTCH1PTPRC
Other Leukemia Subtypes
CD72IL2RASPI1
Leukemia Stem Cell & Proliferation Markers
ADGRG1BAALCBMI1CD33CD34CD44CD47CD96CD99CLEC12ACXCL12CXCR4ERGFCGR2AHAVCR2IL2RAIL3RAKITKLF4LAIR1LIN28AMYCPOU5F1PTPRCSOX2THY1WT1
Possible Prognostic Significance
Indicator of Clinical Outcome in Leukemia
AURKBBAALCBIRC5ERGFOXO3GATA2MECOMMEIS1RUNX1SPI1WT1
Acute Lymphoblastic Leukemia (ALL)
ABCB1AKT1ANPEPBIRC5CD33CD3DCD44FLT3HOXA9IKZF1JUNMMEMYCPAX5SMYD2
B Cell Acute Lymphoblastic Leukemia (B-ALL)
ANPEPCD33CRLF2JUNMS4A1
T Cell Acute Lymphoblastic Leukemia (T-ALL)
BCL11BBMI1LMO1LMO2LYL1MYCTAL1TLX1TLX3
Acute Myeloid Leukemia (AML)
ABCB1ANGPT2BAALCBCL2BIRC2BIRC5BMI1CCNA1CD200CD34CD4CD44CD47CD96CLEC12ACXCL12CXCR4ERGGATA2HAVCR2HGFIL2RAIL3RAKLF4LEF1MECOMMEIS1MN1MYCRUNX1SOX11SOX2SPI1WT1XIAP
Chronic Lymphocytic Leukemia (CLL)
ABCA6ANGPT2BCL2CD24CD38CD69ITGA4KCNN4LAIR1LPLMS4A1MYCNOTCH1ROR1SOX11TTNUGT2B17VPREB3WNT3ZAP70
Chronic Myeloid Leukemia (CML)
AURKAAURKBLIN28AMCL1PTCH1
Chemotherapy Resistance Related
AKT1AURKBBAALCBCL2BIRC2CD274CD274CD44CD47ERGHLA-DRAHLA-DRB1IL3RAMCL1MYCXIAP
Hypoxia & Oxidative Stress Related
ANGPT2VEGFA
Treatment Target or Treatment Indicator
ASS1BMI1CASP8AP2CD33CD47CD69CD96CDC25ACDKN2ACDKN2BCLEC12ACXCR4FLT3FOXM1FOXO3HAVCR2IL3RAITGAMKLF4LMO2MS4A1MYCPTCH1SERPINI1SMARCA4TAL1ZAP70
Associated with Invasiveness or Infiltration into Central Nervous System
CXCL12CXCR4ZAP70
Minimal Residual Disease
ADGRE5BAALCBCL2CD19CD200CD24CD300ACD44CD47CD69CD72CD79BCD86CD99CLEC12AHAVCR2IL2RAIL3RAITGA6NPM1PBX1WT1
Mechanistic Role in Pathogenesis
BCL11BBCL2BMI1ERGFOXM1GATA2HOXA9LMO2LPLMEIS1NOTCH1PAX5SPI1TAL1TLX1TLX3TNFVEGFAWT1
Expression Altered due to Genetic Alterations
Acute Lymphoblastic Leukemia (ALL)
AHI1BCL11ABCL2BCL9BRD4CCND2CEBPACEBPBCEBPDCEBPECEBPGCRLF2EPORETV6HOXA1ID4IGF2BP1IL3IRS4LCKLHX4LMO1LMO2LYL1MYBMYCNKX2-5NOTCH1OLIG2TAL2TLX1TLX3
Acute Myeloid Leukemia (AML)
MECOMNKX2-5RANBP17TCL1ATLX3
Other Leukemia Subtypes & Other Genetic Alterations
BAALCBCL11BCRLF2ERGKITLMO1LPLNPM1TAL1ZAP70
Chronic Neutrophilic Leukemia (CNL)
CSF3R
Multiple Myeloma
ATMBRAFCDKN2AEGFRFBXW7HRASMYCPTENSMARCB1
Myelofibrosis
CHEK2IDH1IDH2SRSF2
Myeloid Malignancies
CBLCBLBDNMT3AEZH2
Other Myeloid Neoplasms
BRAFCDKN2ACUX1FBXW7HRASMYD88PTENSTAT3

Product Resources

icon_0041_download-s Save Target List
icon_0041_download-s Detailed Target List for each Analyte
File Size: 31.27 KBLanguage: English
icon_0245_cc_gen_pdf-s Product Specification Sheet
File Size: 356.86 KBLanguage: English

Resources

Safety Data Sheets (1)
Safety Data Sheets
Kit Handbooks (2)
QIAseq RNA Fusion XP Panel Handbook
PDF (2MB)
QIAseq RNA Fusion XP Panel Handbook UDIs V2
PDF (1MB)
Template Files (1)
QIAseq RNA Fusion XP All-in-One Tool
SOFTWARE (884KB)
Certificates of Analysis (1)
Certificates of Analysis

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